Structure of AMPK bound to activator
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Structure of AMPK bound to activator Descriptor: 1,4:3,6-dianhydro-2-O-(6-chloro-5-{4-[1-(hydroxymethyl)cyclopropyl]phenyl}-1H-benzimidazol-2-yl)-D-mannitol, 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, ... Authors: Calabrese, M.F, Kurumbail, R.G. Deposit date: 2017-01-05 Release date: 2017-05-17 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (3.45 Å) Cite: Activation of Skeletal Muscle AMPK Promotes Glucose Disposal and Glucose Lowering in Non-human Primates and Mice. Cell Metab., 25, 2017
激活剂结合的腺苷酸活化蛋白激酶(AMP-activated protein kinase, AMPK)结构;描述物:1,4:3,6-二脱水-2-O-(6-氯-5-{4-[1-(羟甲基)环丙基]苯基}-1H-苯并咪唑-2-基)-D-甘露醇、5'-腺苷酸活化蛋白激酶催化亚基α-1、5'-腺苷酸活化蛋白激酶亚基β-1……;作者:Calabrese, M.F.、Kurumbail, R.G.;提交日期:2017年1月5日;发布日期:2017年5月17日;最后修改日期:2024年11月20日;实验方法:X射线衍射(分辨率3.45埃);引用文献:《激活骨骼肌AMPK可促进非人灵长类与小鼠的葡萄糖摄取与血糖降低》,《Cell Metab.》,25卷,2017年



