Gene Regulation through the downregulation of H3K9ac induced by heat shock

We investigated the effect of downregulation of H3K9ac induced by heat shock on gene expression in AGS cells, using RNA-seq analysis. We found that heat shock at 43°C resulted in the upregulation of 792 genes and the downregulation of 292 genes in AGS cells Overall design: Comparative gene expression profiling analysis of RNA-seq data for AGS cells treated with or without heat shock at 43°C for 1 h and subsequently upregulated by SAHA treatment