官方服务：
资源简介：
We analyzed the differential genes between PI3K inhibitor resistant strains and their parents
应用场景：
创建时间：
2024-12-31
相关数据集
The crystal structure of the murine class IA PI 3-kinase p110delta in complex with DL07.
The crystal structure of the murine class IA PI 3-kinase p110delta in complex with DL07. Descriptor: 3-{[4-amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]ethynyl}phenol, PHOSPHATIDYLINOSITOL
Protein Data Bank Japan2023-12-20 更新50
Therapeutic Resistance to PI3K-alpha Inhibitors
We have studied the tumor genomic evolution in a patient with metastatic breast cancer bearing an activating PIK3CA mutation. The patient was treated with the PI3Kα inhibitor BYL719 and achieved a las
NIAID Data Ecosystem50
PI3K-Seeker: A Machine Learning-Powered Web Tool to Discover PI3K Inhibitors
Phosphatidylinositol 3-kinases (PI3Ks) play a crucial role in human metabolism, and their dysregulation contributes to the development of several metabolic disorders, including cancer. Despite advance
Figshare2025-11-18 更新30
Gene expression profiling upon PI3K inhibition using different inhibitors
Activation of the phosphoinositide 3-kinase (PI3K)/Akt signaling pathway is one the most frequent genetic events in human cancer. Therefore, the development of PI3K inhibitors has attracted much atten
NIAID Data Ecosystem50
Crystal structure of human PI3K-gamma in complex with Compound 17
Crystal structure of human PI3K-gamma in complex with Compound 17 Descriptor: 2-amino-5-{2-[(1S)-1-cyclopropylethyl]-7-methyl-1-oxo-2,3-dihydro-1H-isoindol-5-yl}-N-(trans-3-hydroxycyclobutyl)pyrazolo[
Protein Data Bank Japan2024-05-22 更新50
