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Crystal structure of spleen tyrosine kinase complexed with R406

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Protein Data Bank Japan2023-09-06 更新2026-03-21 收录
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Crystal structure of spleen tyrosine kinase complexed with R406 Descriptor: 6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one, Tyrosine-protein kinase SYK Authors: Kuglstatter, A, Villasenor, A.G. Deposit date: 2009-01-07 Release date: 2009-03-10 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural insights for design of potent spleen tyrosine kinase inhibitors from crystallographic analysis of three inhibitor complexes. Chem.Biol.Drug Des., 73, 2009
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2009-01-07
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