Catalytic Asymmetric Friedel–Crafts/Protonation of Nitroalkenes and N-Heteroaromatics
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The catalytic asymmetric Friedel–Crafts/protonation of indoles and pyrroles with α-substituted nitroalkenes to give the corresponding adducts in a highly anti-selective manner was achieved by an imidazoline–aminophenol (L2)–Cu complex. The anti-adducts could be successfully transformed to biochemically important α-substituted β-heteroarylalkylamines.
创建时间:
2016-02-23



