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RNA-seq analysis of Mettl3fl/fl and LysM-cre, Mettl3fl/fl MDSC Transcriptomes

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NIAID Data Ecosystem2026-04-30 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP334269
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To comprehensively learn about the mechanisms of METTL3-mediated pro-tumoral functions, we performed RNA-sequencing to identify differentially expressed genes in isolated MDSC in Mettl3fl/fl (WT) and LysM-cre, Mettl3fl/fl (KO) MC38-bearing mice Overall design: RNA-seq profiles of MDSCs in 8 weeks Mettl3fl/fl and LysM-cre, Mettl3fl/fl mice were generated by deep sequencing, with biologic replicates.
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2022-03-25
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