首页/数据集/The m6A demethylase FTO promotes C/EBPÃ-LIP translation to perform oncogenic functions in breast cancer cells (Ribosome profiling)

The m6A demethylase FTO promotes C/EBPÃ-LIP translation to perform oncogenic functions in breast cancer cells (Ribosome profiling)

NIAID Data Ecosystem2026-05-02 收录

乳腺癌翻译调控

FTO基因敲除效应

数据链接：

https://www.ncbi.nlm.nih.gov/sra/ERP168924 数据链接链接失效反馈

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资源简介：

Ribosome profiling (RP) results of MDA-MB-231 cells; two scrambled shRNA control (SCR) replicates and two FTO knockdown (shFTO) replicates.

应用场景：

创建时间：

2025-07-22

核糖体图谱分析

乳腺癌翻译调控

We performed ribosome profiling in cell line models of human breast cancer. We profiled 2 representative estrogen receptor-positive (T47D and ZR75-1) and 2 representative triple negative (SUM159PT and

NIAID Data Ecosystem110

Genome-wide analysis of transcriptome and translatome following eIF4A1 knockdown in MCF7 cells [RNA-Seq]. Homo sapiens

乳腺癌翻译调控

eIF4A1依赖性翻译

To identify which genes were regulated by mRNA helicase activity, the effect of eIF4A1 knockdown on the MCF7 cell transcriptome and translatome was determined. eIF4A1-dependent mRNAs were highly enric

NIAID Data Ecosystem60

Supplementary Table 8 from Eukaryotic Translation Initiation Factor 4E–Induced Progression of Primary Human Mammary Epithelial Cells along the Cancer Pathway Is Associated with Targeted Translational Deregulation of Oncogenic Drivers and Inhibitors

乳腺癌翻译调控

癌基因翻译失调

NIAID Data Ecosystem30

Ribosome profiling on SUM159PT cells grown in vitro or in vivo. Homo sapiens

核糖体分析

乳腺癌翻译调控

SUM159PT cells were grown either in vitro (in culture) or in vivo (mouse), after which RPL10a tagged with GFP was used to perform extraction by immoprecipitation and subsequent ribosome profiling Over

NIAID Data Ecosystem60

Genome-wide analysis of RNAs translationally regulated upon BRCA1 depletion in human mammary epithelial cells

BRCA1翻译调控

乳腺癌翻译调控

Loss of function of the tumor suppressor BRCA1 (Breast Cancer 1) protein is responsible for numerous familial and sporadic breast cancers. We previously identified PABP1 as a novel BRCA1 partner and s

NIAID Data Ecosystem40

The m6A demethylase FTO promotes C/EBPÃ-LIP translation to perform oncogenic functions in breast cancer cells (Ribosome profiling)

资源简介：

相关数据集

The m6A demethylase FTO promotes C/EBPÃ-LIP translation to perform oncogenic functions in breast cancer cells (Ribosome profiling)