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Additional file 1 of Comparative gene expression profiling between optic nerve and spinal cord injury in Xenopus laevis reveals a core set of genes inherent in successful regeneration of vertebrate central nervous system axons

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Figshare2020-08-06 更新2026-04-08 收录
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Additional file 1. Cuffdiff2 differential expression data. Tabs are for each injury condition and time point vs. their relevant controls (N = 3 biological replicates, each). Tabs PW1–3) Tadpole spinal cord injury (SCI) hindbrain vs. age-matched, unoperated control hindbrain at 3 days, 1 week, and 3 weeks, respectively; PW4–6) Juvenile frog SCI hindbrain at 3 days, 1 week, and 3 weeks vs. unoperated control hindbrain; PW7–9) juvenile frog optic nerve crush (ONC) eye vs. the contralateral unoperated eye at 3 days, 11 days, and 3 weeks, respectively. Abbreviations: chr, chromosome; cntrl, control; FPKM, fragments per kilobase of transcript per million mapped reads; ONC, optic nerve crush; p, the calculated probability for a single given gene that the observed difference represented no change in expression (i.e., log2(fold change) = 0); q, false discovery rate-adjusted (FDR) p-value [14]; significant, “yes” if q
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2020-08-06
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