Demographic, clinical and analytical characteristics of patients.

Data are expressed as mean (standard deviation), median [percentiles 25th–75th] or absolute number (percentage).ACEI = angiotensin-converting enzyme inhibitor; ARB = angiotensin II receptor blocker; BMI = body mass index; COPD: Chronic obstructive pulmonary disease; eGFR = estimated glomerular filtration rate; HF, heart failure; hs-cTnT, high-sensitivity circulating troponin T; ST2 = high-sensitivity soluble ST2; LVEF = left ventricular ejection fraction; NT-proBNP = N-terminal pro-brain natriuretic peptide; NYHA = New York Heart Association. CRT = cardiac resynchronization therapy; ICD = implantable cardiac defibrillator.Ref. = Reference.Loop diuretic dose 1: Furosemide-equivalent dose up to 40 mg/day or Torasemide up to 10 mg/day.Loop diuretic dose 2: Furosemide-equivalent dose >40 mg/day or Torasemide>10 mg/day.The logarithmic functions of NTproBNP, hs-cTnT and cystatin C, the quadratic term of the logarithmic function of hs-cTnT, ST2 as ST2/10 and the quadratic term of ST2/10 were used in the Cox models. P value for (ST2/10)22