List of attenuated <i>B</i>. <i>melitensis</i> genes <i>in vitro</i> and in mice conditions.
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Page 1: List of the 3369 genes of B. melitensis. Each gene is associated with the value of TnIF in the 2YT, lungs and spleen conditions as well as the value of ΔTnIF associated with the lungs and spleen conditions. Page 2: List of 2460 genes that are not predicted to induce a growth defect in 2YT (TnIF > 2.7 in 2YT condition). Page 3: List of 135 genes predicted to cause attenuation in the lungs of wild type mice (ΔTnIF < -0.5 in lungs condition). Page 4: List of 257 genes predicted to cause attenuation in the spleen of wild type mice (ΔTnIF < -0.5 in spleen condition). Page 7: List of the 4 genes selected as vaccine candidates showing strong attenuation in the spleen (dTnIF < -2.0 in spleen condition). Page 8: List of the 17 genes selected as vaccine candidates showing moderate attenuation in the spleen (dTnIF < -1.0). (XLSX)
