Human Erk2 with an Erk1/2 inhibitor
收藏Protein Data Bank Japan2024-05-08 更新2026-03-21 收录
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https://pdbj.org/mine/summary/5nho
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资源简介：
Human Erk2 with an Erk1/2 inhibitor Descriptor: (6~{S})-5-(2-methoxyethyl)-6-methyl-2-[5-methyl-2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-6,7-dihydro-1~{H}-pyrrolo[3,2-c]pyridin-4-one, Mitogen-activated protein kinase 1, SULFATE ION Authors: Debreczeni, J.E, Ward, R.A, Bethel, P, Cook, C, Davies, E, Eckersley, K, Fairley, G, Feron, L, Flemington, V, Graham, M.A, Greenwood, R, Hopcroft, P, Howard, T.D, Hudson, J, James, M, Jones, C.D, Jones, C.R, Lamont, S, Lewis, R, Lindsay, N, Roberts, K, Simpson, I, StGallay, S, Swallow, S, Tonge, M. Deposit date: 2017-03-22 Release date: 2017-04-19 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.24 Å) Cite: Structure-Guided Discovery of Potent and Selective Inhibitors of ERK1/2 from a Modestly Active and Promiscuous Chemical Start Point. J. Med. Chem., 60, 2017
创建时间：
2017-03-22
