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Transcriptional changes in murine keratinocyte harbouring heterozygous or homozygous R245W p53 mutation in vitro

ChEBI2018-10-31 更新2026-07-12 收录

p53基因突变功能研究

角质形成细胞转录组学

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-4941 数据链接链接失效反馈

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资源简介：

Transcriptional changes in murine keratinocyte harbouring heterozygous or homozygous R245W p53 mutation in vitro

应用场景：

创建时间：

2018-10-31

皮肤炎症机制

角质形成细胞转录组学

Interleukin-1 is a proinflammatory and immunomodulatory cytokine that plays a crucial role in inflammatory diseases of the skin, including bacterial infections, bullous diseases, UV damage and especia

NIAID Data Ecosystem100

âTranscriptomics Analysis Of SOCS3-deficient keratinocytes: Reveled Insights Into Progression of Chronic Skin Disease

疾病分子机制

角质形成细胞转录组学

We analyzed time series transcriptomics data of SOCS3 conditional knockout keratinocytes mice at 2, 8 and 10 week by using RNA-Sequencing technology to gain a basic understanding on the role of SOCS3

NIAID Data Ecosystem80

Keratinocyte response to SNHG26 silencing

角质形成细胞转录组学

非编码RNA功能

Analysis the transcriptome of keratinocyte after SNHG26 silencing with or without TNFa treatment for 3 hours. SNHG26 is a conseved lncRNA which is upregulated in the epidermis of human and mouse acute

NIAID Data Ecosystem30

Next Generation Sequencing Facilitates Quantitative Analysis of Primary Keratinocytes and OSM-treated Primary Keratinocytes Transcriptomes. Next Generation Sequencing Facilitates Quantitative Analysis of Primary Keratinocytes and OSM-treated Primary Keratinocytes Transcriptomes

角质形成细胞转录组学

刺激响应

Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this study are to compare transcriptome profiling (RNA-seq) between Primary Kerat

NIAID Data Ecosystem90

Different response of WT and Ts keratinocyte to TPA treatment

皮肤细胞药物反应

角质形成细胞转录组学

Ts keratinocyte has increased proliferation compare to WT keratinocyte upon TPA treatment. This result showed the different transcription regulation in Ts and WT keratinocyte upon TPA treatment. Total

NIAID Data Ecosystem40

Transcriptional changes in murine keratinocyte harbouring heterozygous or homozygous R245W p53 mutation in vitro

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