Type 2 innate lymphoid cells (ILC2s) play a pivotal role in type 2 asthma. CD226 is a costimulatory molecule involved in various inflammatory diseases. Here, we aimed to investigate CD226 expression a

NIAID Data Ecosystem40

IMPACT OF AGING ON THE DEVELOPMENT OF ASTHMA PHENOTYPES

哮喘病理机制

年龄依赖性免疫反应

Asthma is the most common chronic disease of childhood, in which infectious and allergic agents trigger airway inflammation leading to respiratory symptoms. Although generally viewed as a life-long di

NIAID Data Ecosystem10

IL-33 induces an antiviral signature in mast cells but enhances their permissiveness for human rhinovirus infection

病毒-宿主相互作用

哮喘病理机制

Mast cells (MCs) are classically associated with allergic asthma but their role in antiviral immunity is unclear. Human rhinoviruses (HRVs) are a major cause of asthma exacerbations and can infect and

NIAID Data Ecosystem40

Table_1_Neonatal LPS Administered Before Sensitization Reduced the Number of Inflammatory Monocytes and Abrogated the Development of OVA-Induced Th2 Allergic Airway Inflammation.pdf

哮喘病理机制

早期生命免疫调节

It is becoming increasingly clear that environment factors during early life play a pivotal role in the development of allergic asthma. Among these, a traditional farm is one of the strongest protecti

NIAID Data Ecosystem20

Phenotypic responses of differentiated asthmatic human airway epithelial cultures to rhinovirus

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