Proteomic analysis of meninges from autoimmune encephalitis (mouse model)
收藏国家人口健康科学数据中心2026-06-01 收录
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We developed a B-cell-mediated mouse model of Anti-N-Methyl-D-aspartate receptor autoimmune encephalitis (AE) by immunization with a GluN1359–378 peptide. In our model, mice display a series of symptoms that recapitulate autoimmune encephalitis such as anxiety behaviour and spatial memory impairment (Wagnon et al, Brain 2020) . Proteomic analysis of AE meninges showed enrichment of differentially expressed proteins in biological processes associated with B cell activation and cytokine signalling pathways.
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北京蛋白质组研究中心创建时间：
2024-11-12
