Crystal Structure of SIRT2 in complex with the macrocyclic peptide S2iL5

Crystal Structure of SIRT2 in complex with the macrocyclic peptide S2iL5 Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, NAD-dependent protein deacetylase sirtuin-2, ... Authors: Yamagata, K, Nishimasu, H, Ishitani, R, Nureki, O. Deposit date: 2013-06-06 Release date: 2014-02-19 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.518 Å) Cite: Structural Basis for Potent Inhibition of SIRT2 Deacetylase by a Macrocyclic Peptide Inducing Dynamic Structural Change Structure, 22, 2013与大环肽S2iL5结合的沉默信息调节因子2（SIRT2）晶体结构；描述项：1,2-乙二醇、2-(N-吗啉代)乙磺酸、烟酰胺腺嘌呤二核苷酸（NAD）依赖的蛋白去乙酰化酶沉默信息调节因子2（SIRT2）等；作者：Yamagata K、Nishimasu H、Ishitani R、Nureki O；入库日期：2013-06-06；发布日期：2014-02-19；最后修改日期：2023-11-08；实验方法：X射线衍射（分辨率2.518埃）；引用文献：《通过诱导动态结构变化的大环肽强效抑制SIRT2脱乙酰酶的结构基础》，Structure，第22卷，2013年