Gene expression change after Enzalutamide treatment in MCF7 cells

To explore the mechanism of action of Enzalutamide, we performed RNA-seq to investigate gene expression difference after Enzalutamide treatment in both MCF7 and MCF7 with AR over expression (AROE) cells. RNA-sequencing (RNA-seq) of MCF7 and MCF7 AROE cells with DMSO or Enzalutamide treatment Overall design: RNA-seq were performed under four conditions, DMSO treatment in parental MCF7 cells, Enzalutamide treatment in parental MCF7 cells, DMSO treatment in AROE MCF7 cells and Enzalutamide treatment in AROE MCF7 cells.