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Analysis of a new family of widely distributed metal-independent alpha mannosidases provides unique insight into the processing of N-linked glycans, Clostridium perfringens CPE0426 complexed with alpha-1,6-linked 1-thio-alpha-mannobiose

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Analysis of a new family of widely distributed metal-independent alpha mannosidases provides unique insight into the processing of N-linked glycans, Clostridium perfringens CPE0426 complexed with alpha-1,6-linked 1-thio-alpha-mannobiose Descriptor: 1,2-ETHANEDIOL, Putative uncharacterized protein CPE0426, alpha-D-mannopyranose-(1-6)-6-thio-alpha-D-mannopyranose Authors: Gregg, K.J, Zandberg, W.F, Hehemann, J.-H, Whitworth, G.E, Deng, L.E, Vocadlo, D.J, Boraston, A.B. Deposit date: 2011-02-22 Release date: 2011-03-09 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Analysis of a New Family of Widely Distributed Metal-independent {alpha}-Mannosidases Provides Unique Insight into the Processing of N-Linked Glycans. J.Biol.Chem., 286, 2011

本数据集围绕一类广泛分布的金属非依赖性α-甘露糖苷酶(alpha mannosidases)新家族展开分析,为N-连接糖链(N-linked glycans)的加工过程提供了独特研究视角。所涉复合物为产气荚膜梭菌(Clostridium perfringens)CPE0426与α-1,6连接的1-硫代-α-甘露二糖形成的复合体;该结构的标注物为1,2-乙二醇,样本蛋白为推定未表征蛋白CPE0426,配体全称为α-D-吡喃甘露糖-(1-6)-6-硫代-α-D-吡喃甘露糖。作者:Gregg K.J.、Zandberg W.F.、Hehemann J.-H.、Whitworth G.E.、Deng L.E.、Vocadlo D.J.、Boraston A.B.。提交日期:2011年2月22日;发布日期:2011年3月9日;最后修改日期:2024年2月21日。实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率2.05埃(Å)。引用文献:《一类广泛分布的金属非依赖性α-甘露糖苷酶新家族的分析为N-连接糖链加工提供独特见解》,《生物化学杂志》(J. Biol. Chem.),第286卷,2011年。
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2011-02-22
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