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We retrospectively analyzed 659 patients with chronic hepatitis B virus(HBV) infection and 410 patients in our medical center, from October, 2015 to December, 2017. We set 659 CHB patients as training set, and 410 patients with other chronic liver diseases as validation set. Logistic regression analysis between the conventional markers and the performances of GOV detected by endoscopy were assessed. A new algorithm for diagnosing GOV was established and its sensitivity and specificity for predicting the varices was verified.
本研究于2015年10月至2017年12月期间,在本医疗中心回顾性分析了659例慢性乙型肝炎病毒(HBV)感染患者及410例慢性肝病患者。本研究将659例慢性乙型肝炎(Chronic Hepatitis B,CHB)患者设为训练集,将其余410例慢性肝病患者划分为验证集。本研究对常规标志物与内镜检出的胃食管静脉曲张(Gastric Esophageal Varices,GOV)表现特征之间的相关性开展了逻辑回归分析。本研究构建了一种用于诊断GOV的新型算法,并验证了该算法预测静脉曲张的灵敏度与特异度。




