Structural Analysis of the Unmutated Ancestor of the HIV-1 Envelope V2 Region Antibody CH58 Isolated From an RV144 HIV-1 Vaccine Efficacy Trial Vaccinee and Associated with Decreased Transmission Risk

Structural Analysis of the Unmutated Ancestor of the HIV-1 Envelope V2 Region Antibody CH58 Isolated From an RV144 HIV-1 Vaccine Efficacy Trial Vaccinee and Associated with Decreased Transmission Risk Descriptor: CH58-UA Fab heavy chain, CH58-UA Fab light chain, Envelope glycoprotein Authors: Nicely, N.I, Wiehe, K, Kepler, T.B, Jaeger, F.H, Dennison, S.M, Liao, H.-X, Alam, S.M, Hwang, K.-K, Bonsignori, M, Rerks-Ngarm, S, Nitayaphan, S, Pitisuttithum, P, Kaewkungwal, J, Robb, M.L, O'Connell, R.J, Michael, N.L, Kim, J.H, Haynes, B.F. Deposit date: 2014-10-07 Release date: 2015-08-12 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural analysis of the unmutated ancestor of the HIV-1 envelope V2 region antibody CH58 isolated from an RV144 vaccine efficacy trial vaccinee. EBioMedicine, 2, 2015

从RV144 人类免疫缺陷病毒1型（HIV-1）疫苗效力试验受试者中分离得到、且与传播风险降低相关的HIV-1包膜V2区抗体CH58未突变祖先的结构分析
数据集标识：CH58-UA 抗原结合片段（Fab）重链、CH58-UA Fab轻链、包膜糖蛋白
作者：Nicely, N.I、Wiehe, K、Kepler, T.B、Jaeger, F.H、Dennison, S.M、Liao, H.-X、Alam, S.M、Hwang, K.-K、Bonsignori, M、Rerks-Ngarm, S、Nitayaphan, S、Pitisuttithum, P、Kaewkungwal, J、Robb, M.L、O'Connell, R.J、Michael, N.L、Kim, J.H、Haynes, B.F.
提交日期：2014年10月7日
发布日期：2015年8月12日
最后修改日期：2024年11月27日
检测方法：X射线衍射（2.3埃）
引用文献：从RV144 人类免疫缺陷病毒1型（HIV-1）疫苗效力试验受试者中分离得到的HIV-1包膜V2区抗体CH58未突变祖先的结构分析，《EBioMedicine》，第2卷，2015年