CryoEM Structure of the active Adrenomedullin 1 receptor G protein complex with adrenomedullin peptide

CryoEM Structure of the active Adrenomedullin 1 receptor G protein complex with adrenomedullin peptide Descriptor: ADM, Calcitonin gene-related peptide type 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Belousoff, M.J, Liang, Y.L, Sexton, P, Danev, R. Deposit date: 2019-10-30 Release date: 2020-03-25 Last modified: 2025-06-04 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structure and Dynamics of Adrenomedullin Receptors AM1and AM2Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity-Modifying Proteins. Acs Pharmacol Transl Sci, 3, 2020

活性肾上腺髓质素1受体G蛋白复合物与肾上腺髓质素肽的冷冻电镜（CryoEM）结构
描述符：ADM（Adrenomedullin）、降钙素基因相关肽1型受体、鸟苷酸结合蛋白G(I)/G(S)/G(O)亚基γ-2……
作者：Belousoff M.J.、Liang Y.L.、Sexton P.、Danev R.
提交日期：2019-10-30
发布日期：2020-03-25
最后修改日期：2025-06-04
方法：电子显微镜（分辨率3 Å）
引用文献：《肾上腺髓质素受体AM1与AM2的结构与动力学揭示受体活性修饰蛋白调控受体表型的关键机制》，刊载于《ACS药理学与转化科学（ACS Pharmacol Transl Sci）》，2020年，第3卷。