Genome-wide association studies (GWAS) have hitherto identified several germline variants associated with cancer susceptibility, but the molecular functions of these risk modulators remain largely unc
Table S2. Filtered variants detected in three or more patients. Chromosome, start, end - genome coordinates of variant; Ref/Alt - reference/alternative variant sequence. GT - genotype detected in a gi
As a genetic disease, cancer is caused by the activation of oncogenes and the inhibition of tumor suppressor genes via genetic and epigenetic mechanisms. Given the important role of energy metabolism