Genome-wide association study Summary statistics of Invasive melanoma vs controls, In situ Melanoma vs controls and In situ vs invasive melanoma (case-case)

Genome-wide association study Summary statistics of Invasive melanoma vs controls, In situ Melanoma vs controls and In situ vs invasive melanoma (case-case). The first GWAS meta-analysis combines GWAS summary statistics of invasive melanoma from UK Biobank (as of August 2022), FinnGen release 9, QSkin Sun and Health Study and The Queensland Study of Melanoma: environmental and genetic associations (Q-MEGA) study.

The second GWAS meta-analysis combines GWAS summary statistics of in situ melanoma from UK Biobank (as of August 2022), FinnGen release 9, QSkin Sun and Health Study and The Queensland Study of Melanoma: environmental and genetic associations (Q-MEGA) study.

The third GWAS meta-analysis combines GWAS summary statistics of in situ vs invasive (case-case; in situ code 0, invasive code 1) melanoma from UK Biobank (as of August 2022), QSkin Sun and Health Study and The Queensland Study of Melanoma: environmental and genetic associations (Q-MEGA) study.

Columns

CHR Chromosome

SNP rsid

POS Base position HG Build 37

A1 effect allele

A2 Non-effect allele

A1FREQ Allele frequency of effect allele

BETA effect estimate of effect allele

SE standard error of effect estimate

PVAL two-tailed p value

DIRECTION the Direction of effect of the SNP in each cohort ( in the order UKBB, FINNGEN, QSKIN, QMEGA 610k, QMEGA OMNI)

N sample size

See