Physiologic RNA Targets and Refined Sequence Specificity of Coronavirus EndoU
收藏NIAID Data Ecosystem2026-03-12 收录
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资源简介：
Coronavirus EndoU inhibits double-stranded RNA (dsRNA)-activated antiviral responses; however, it is unclear how this occurs because the physiologic RNA substrates of EndoU are unknown. In this study, we used Mouse Hepatitis Virus (MHV)-infected bone-marrow-derived macrophage (BMM) and cyclic phosphate cDNA sequencing to identify the RNA targets of EndoU Overall design: cyclic phosphate and RNA seqeuncing libraries generated from MHV infected bone marrow macrophages.
创建时间：
2020-12-19
