Mouse cGAS bound to the inhibitor RU332
收藏Protein Data Bank Japan2024-03-13 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/5xze
下载链接
链接失效反馈官方服务：
资源简介：
Mouse cGAS bound to the inhibitor RU332 Descriptor: (3R)-3-[1-(3H-1lambda~4~,3-benzothiazol-2-yl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]-2-benzofuran-1(3H)-one, Cyclic GMP-AMP synthase, DNA (5'-D(*AP*AP*AP*TP*TP*GP*CP*CP*GP*AP*AP*GP*AP*CP*G)-3'), ... Authors: Vincent, J, Adura, C, Gao, P, Luz, A, Lama, L, Asano, Y, Okamoto, R, Imaeda, T, Aida, J, Rothamel, K, Gogakos, T, Steinberg, J, Reasoner, S, Aso, K, Tuschl, T, Patel, D.J, Glickman, J.F, Ascano, M. Deposit date: 2017-07-12 Release date: 2017-10-11 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.177 Å) Cite: Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice. Nat Commun, 8, 2017
创建时间：
2017-07-12
