Data for: Genomic heterozygosity is associated with parasite abundance, but the effects are not mediated by host condition

Whether, when, and how genetic diversity buffers individuals and populations against infectious disease risk is a critical and open question for understanding wildlife disease and zoonotic disease risk. Several, but not all, studies have found negative relationships between infection and heterozygosity in wildlife. Since they can host multiple zoonotic infections, we sampled a population of wild deer mice (Peromyscus maniculatus), sequenced their genomes, and examined their fecal samples for coccidia and nematode eggs. We analyzed coccidia infection status, abundance, and coinfection status in relation to per-locus and per-individual measures of heterozygosity, as well as identified SNPs associated with infection status. Since heterozygosity might affect host condition, and condition is known to affect immunity, it was included as a co-variate in the per-individual analyses and as response variable in relation to heterozygosity. Not only did coccidia-infected individuals have lower leve..., Field sampling methods
Deer mice (Peromyscus maniculatus) were live-trapped at the Bernard Field Station in Claremont, CA from June 27 to August 9, 2019. Eight 40 × 40 m grids with traps spaced 10 m apart (25 traps/grid) were established in paired locations throughout the sage-scrub habitat. At each grid, Sherman traps were baited with seeds for three nights in a row. Three-night trapping sessions were repeated at each grid every two weeks. Upon their first capture each session, mice were weighed, measured, and a retro-orbital blood sample was collected. Each mouse was also given an individually-numbered ear tag upon its first capture. Females were considered reproductive if they were pregnant or lactating, and males were classified as reproductive based on testes size. Fecal samples from each individual were collected from the traps, weighed, and stored in neutral-buffered formalin. Blood samples were kept on ice, then spun at 2000 g for 10 min to separate plasma. Plasma and pellet fra..., BFS 2019 - rodent infection heterozygosity data.csv contains capture data, infection data and heterozygosity data.
Capture data: Trapping grid (GRID), grid site (Grid2), trap number (Trap), Species (PM = Peromyscus maniculatus), Sex (F = female, M = male),  Age (A = adult, SA = subadult), reproductive characteristics (VAG = perforate vagina, NIP = enlarged nipples indicative of lactation, PREG = pregnant, TES = enlarged testes, Repro = reproductive status, total length in mm, body length in mm, and weight in g. 
Infection data: Coccidia oocysts per gram of feces at initial capture (Init.Coccidia.EPG, and log transformed in logCoccidiaEPG), nematode eggs per gram of feces at initial capture (Init.Nem.EPG and log transformed in logNemEPG), binary infected with coccidia or not (Infection.Status), coinfection status (Coinf.status), Coccidia severity (Coccidia.group), and length-weight residual condition (condition)
Individual-level heterozygosity data: Number of sites analyzed (N_SITES), ex...