Figure S1 - Repressive Effect of Primary Virus Replication on Superinfection Correlated with Gut-Derived Central Memory CD4⁺ T Cells in SHIV-Infected Chinese Rhesus Macaques

No correlation of superinfection with CD4+ T-cell counts and the percentages of memory CD4+ T cells from peripheral blood (PBL) prior to SHIV-1157ipd3N4 inoculation. (A) Kinetics of CD4+ T-cell counts from PBL for twelve monkeys after primary infection and superinfection. (B) Correlation between the AUC of SHIV-1157ipd3N4 following superinfection and CD4+ T-cell counts from PBL prior to SHIV-1157ipd3N4 inoculation (Pearson's correlation test, R = 0.152, P>0.05). (C) No difference of the percentage of CD4+ Tcm or Tem cells in CD3+ T cells from PBL between SIS (red bars) and SIR monkeys (black bars) prior to SHIV-1157ipd3N4 inoculation (Mann-Whitney U test, P>0.05). (DOC)