Human hypoxanthine guanine phosphoribosyltranserfase in complex with (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)guanine
收藏Protein Data Bank Japan2023-11-01 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/3gep
下载链接
链接失效反馈官方服务：
资源简介：
Human hypoxanthine guanine phosphoribosyltranserfase in complex with (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)guanine Descriptor: Hypoxanthine-guanine phosphoribosyltransferase, {[(1S)-2-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-1-(hydroxymethyl)ethoxy]methyl}phosphonic acid Authors: Guddat, L.W, Keough, D.T, Jersey, J. Deposit date: 2009-02-25 Release date: 2009-08-18 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: a new class of antimalarial therapeutics. J.Med.Chem., 52, 2009
与(S)-9-(3-羟基-2-膦酰甲氧基丙基)鸟嘌呤结合的人次黄嘌呤鸟嘌呤磷酸核糖转移酶（hypoxanthine-guanine phosphoribosyltransferase）
描述项：次黄嘌呤鸟嘌呤磷酸核糖转移酶，{[(1S)-2-(2-氨基-6-氧代-1,6-二氢-9H-嘌呤-9-基)-1-(羟甲基)乙氧基]甲基}膦酸
作者：Guddat L.W.、Keough D.T.、Jersey J.
提交日期：2009-02-25
发布日期：2009-08-18
最后修改日期：2023-11-01
实验方法：X射线衍射（分辨率2.6 Å）
引用文献：《无环核苷膦酸酯类对次黄嘌呤鸟嘌呤磷酸核糖转移酶的抑制作用：一类新型抗疟治疗药物》，《药物化学杂志》，52卷，2009年
创建时间：
2009-02-25
