X-ray crystal structure of beta secretase complexed with compound 8b

X-ray crystal structure of beta secretase complexed with compound 8b Descriptor: Beta-secretase 1, DIMETHYL SULFOXIDE, IODIDE ION, ... Authors: Patel, S. Deposit date: 2007-01-10 Release date: 2007-03-13 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Application of fragment screening by X-ray crystallography to the discovery of aminopyridines as inhibitors of beta-secretase. J.Med.Chem., 50, 2007本数据集为与化合物8b结合的β分泌酶X射线晶体结构。描述符：β分泌酶1（Beta-secretase 1）、二甲基亚砜（DIMETHYL SULFOXIDE）、碘离子（IODIDE ION）等。作者：Patel, S.。提交日期：2007-01-10，发布日期：2007-03-13，末次修改日期：2024-11-20。实验方法：X射线衍射法（X-RAY DIFFRACTION），分辨率2.35埃（Å）。引用文献：《X射线晶体学片段筛选法在氨基吡啶类β分泌酶抑制剂发现中的应用》，《J.Med.Chem.》，第50卷，2007年