Nppb

ENCODES a protein that exhibits hormone activity; hormone receptor binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN cell growth involved in cardiac muscle cell development; cellular response to mechanical stimulus; heart development; PARTICIPATES IN brain natriuretic peptide signaling pathway; ASSOCIATED WITH cardiac hypertrophy; hypertension; increased urine protein level; ASSOCIATED WITH acute kidney failure; Cardiomegaly; congestive heart failure; FOUND IN extracellular space; perinuclear region of cytoplasm; protein-containing complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine; 3,3',4,4',5-pentachlorobiphenyl

编码一种表现出激素活性的蛋白质；激素受体结合（同源）；信号受体结合（同源）；参与细胞生长，涉及心肌细胞发育；对机械刺激的细胞反应；心脏发育；参与脑钠肽信号通路；与心脏肥大、高血压、尿液蛋白质水平升高相关；与急性肾衰竭、心肥大、充血性心力衰竭相关；存在于细胞外空间；细胞质核周区域；蛋白质复合物（同源）；与2,3,7,8-四氯二苯并-对-二恶英、3'-氨基-3'-脱氧-N(6),N(6)-二甲基腺苷、3,3',4,4',5-五氯联苯相互作用。