DNA methylation in skeletal muscle of patients with hypertension and diabetes undergoing coronary artery bypass grafting surgery

Patients with hypertension alone, hypertension plus controlled diabetes and hypertension plus uncontrolled diabetes, and control patients without these conditions underwent coronary artery bypass grafting surgery. Skeletal muscle biopsy specimens were taken at the beginning ('pre-operative') and at the end ('post-operative') of the surgery. 4 patients per each of the 4 groups: control, hypertension only, hypertension plus controlled diabetes and hypertension plus uncontrolled diabetes. Each patient was sampled twice: before and after surgery.