Glycogen Phosphorylase in complex with KS172

Glycogen Phosphorylase in complex with KS172 Descriptor: (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-[5-[4-(trifluoromethyl)phenyl]-4~{H}-1,2,4-triazol-3-yl]oxane-3,4,5-triol, Glycogen phosphorylase, muscle form, ... Authors: Kyriakis, E, Stravodimos, G.A, Kantsadi, A.L, Chatzileontiadou, D.S.M, Leonidas, D.D. Deposit date: 2017-09-05 Release date: 2018-02-28 Last modified: 2025-04-09 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Probing the beta-pocket of the active site of human liver glycogen phosphorylase with 3-(C-beta-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors. Bioorg. Chem., 77, 2018与KS172结合的糖原磷酸化酶（Glycogen Phosphorylase） 描述符：(2R,3S,4R,5R,6S)-2-(羟甲基)-6-[5-[4-(三氟甲基)苯基]-4H-1,2,4-三唑-3-基]四氢吡喃-3,4,5-三醇，肌肉型糖原磷酸化酶，…… 作者：Kyriakis, E、Stravodimos, G.A、Kantsadi, A.L、Chatzileontiadou, D.S.M、Leonidas, D.D. 提交日期：2017-09-05 发布日期：2018-02-28 最后更新：2025-04-09 实验方法：X射线衍射（1.85埃） 引用文献：以3-(C-β-D-吡喃葡萄糖基)-5-(4-取代苯基)-1,2,4-三唑类抑制剂探究人肝糖原磷酸化酶活性位点β口袋的研究，《Bioorg. Chem.》，第77卷，2018年