Structure of the endothelial nitric oxide synthase heme domain in complex with 6-{[(3R,4R)-4-(2-{[(2R/2S)-1-(3-fluorophenyl)propan-2-yl]amino}ethoxy)pyrrolidin-3-yl]methyl}-4-methylpyridin-2-amine

Structure of the endothelial nitric oxide synthase heme domain in complex with 6-{[(3R,4R)-4-(2-{[(2R/2S)-1-(3-fluorophenyl)propan-2-yl]amino}ethoxy)pyrrolidin-3-yl]methyl}-4-methylpyridin-2-amine Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, 6-{[(3R,4R)-4-(2-{[(2R)-1-(3-fluorophenyl)propan-2-yl]amino}ethoxy)pyrrolidin-3-yl]methyl}-4-methylpyridin-2-amine, ACETATE ION, ... Authors: Li, H, Delker, S.L, Poulos, T.L. Deposit date: 2011-04-28 Release date: 2012-05-02 Last modified: 2026-08-12 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Cyclopropyl- and methyl-containing inhibitors of neuronal nitric oxide synthase. Bioorg.Med.Chem., 21, 2013内皮型一氧化氮合酶（endothelial nitric oxide synthase）血红素结构域与6-{[(3R,4R)-4-(2-{[(2R/2S)-1-(3-氟苯基)丙-2-基]氨基}乙氧基)吡咯烷-3-基]甲基}-4-甲基吡啶-2-胺的复合物结构 描述：5,6,7,8-四氢生物蝶呤、6-{[(3R,4R)-4-(2-{[(2R)-1-(3-氟苯基)丙-2-基]氨基}乙氧基)吡咯烷-3-基]甲基}-4-甲基吡啶-2-胺、乙酸根离子…… 作者：Li, H、Delker, S.L.、Poulos, T.L. 存档日期：2011-04-28 发布日期：2012-05-02 最后修改日期：2023-09-13 实验方法：X射线衍射（2.35埃） 引用文献：神经元型一氧化氮合酶（neuronal nitric oxide synthase）的环丙基与甲基类抑制剂。《Bioorg.Med.Chem.》，21卷，2013年