ADAR1-mediated A-to-I RNA editing is essential for erythropoiesis
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ADAR1-mediated A-to-I RNA editing is essential for erythropoiesis
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创建时间：
2016-07-24
相关数据集
Table_1_Erythroid Differentiation and Heme Biosynthesis Are Dependent on a Shift in the Balance of Mitochondrial Fusion and Fission Dynamics.DOCX
Erythropoiesis is the most robust cellular differentiation and proliferation system, with a production of ∼2 × 1011 cells per day. In this fine-tuned process, the hematopoietic stem cells (HSCs) gener
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Full set of E. coli RNA editing assays.
Full table of results for all individual E. coli RNA editing assays including standard deviations. C-to-U RNA editing frequencies are given as 100% when no remaining cytidine signal was detectable upo
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Human Adenosine Deaminase Acting on dsRNA (ADAR2) bound to dsRNA sequence derived from S. cerevisiae BDF2 gene with AC mismatch at reaction site
Human Adenosine Deaminase Acting on dsRNA (ADAR2) bound to dsRNA sequence derived from S. cerevisiae BDF2 gene with AC mismatch at reaction site
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ATAC-seq reveals GATA-1- and heme-dependent chromatin targeting in erythroid cells.
CRISPR/Cas9-mediated ablation of two Alas2 intronic cis-elements in G1E-ER-GATA1 cells strongly reduced GATA-1-induced Alas2 transcription, heme biosynthesis, and GATA-1 regulation of other vital cons
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Disruption in A-to-I editing levels affects C. elegans development more than a complete lack of editing
A-to-I RNA editing is widespread in eukaryotic transcriptomes and plays an essential role in the creation of proteomic and phenotypic diversity. Loss of ADARs, the proteins responsible for A-to-I edit
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