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Cryptoyunnanones A–H, Complex Flavanones from Cryptocarya yunnanensis

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Figshare2021-07-20 更新2026-04-28 收录
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https://figshare.com/articles/dataset/Cryptoyunnanones_A_H_Complex_Flavanones_from_i_Cryptocarya_yunnanensis_i_/15023139
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Eight new complex flavanones with a novel linkage, cryptoyunnanones A–H (1–8), together with four known α-pyrones, were isolated from the leaves and twigs of Cryptocarya yunnanensis. The structures of 1–8 including their absolute configurations were characterized by spectroscopic data analysis and single-crystal X-ray crystallography. Plausible biosynthetic pathways for the formation of compounds 1–8 were proposed. Compounds 1–4 exhibited cytotoxicity against HCT-116, MDA-MB-231, and PC-3 cancer cells with IC50 values from 6.4 to 9.1 μM.
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2021-07-20
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