Mechanistic Studies of the Rhodium NHC Catalyzed Hydrodefluorination of Polyfluorotoluenes
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https://figshare.com/articles/dataset/Mechanistic_Studies_of_the_Rhodium_NHC_Catalyzed_Hydrodefluorination_of_Polyfluorotoluenes/2237233
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资源简介：
The six-membered-ring NHC complexes
Rh(6-NHC)(PPh3)2H (6-NHC = 6-iPr (1),
6-Et (2), 6-Me (3)) have been employed in
the catalytic hydrodefluorination (HDF) of C6F5CF3 and 2-C6F4HCF3. Stoichiometric
studies showed that 1 reacted with C6F5CF3 at room temperature to afford cis- and trans-phosphine isomers of Rh(6-iPr)(PPh3)2F (4), which re-form 1 upon heating with Et3SiH. Although up to three
consecutive HDF steps prove possible with C6F5CF3, the ultimate effectiveness of the catalysts is limited
by their propensity to undergo C–H activation of partially
fluorinated toluenes to give, for example, Rh(6-iPr)(PPh3)2(C6F4CF3) (7), which was isolated and structurally characterized.
创建时间：
2016-02-16
