Epigenetic profiling in 4 cohorts of pancreatic cancer patients revealed reduced expression of the chromatin factor inhibitor of growth family member 3 (ING3). Furthermore, using mass spectrometry ana
Abnormal differentiation contributes to the spectrum of aberrant properties of tumor cells. Differentiation of both normal and tumor cells is controlled by regulatory networks enforced by transcriptio
In order to better study the differences between pancreatic cancer patients' tumor tissues and their adjacent tissues, we compared chromatin accessibility of pancreatic cancer tumor tissues and adjace
Additional file 5. Loops identified by in situ Hi-C. (A) Loops in three cell lines. (B) Genes looped to Capan-1 specific enhancers, compared with PANC-1. (C) GO enrichment analysis of genes looped to
