Genome-wide transcriptional analysis of human patterned induced neurons (hpiNs)
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE112732
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资源简介：
We report that combining NGN2 programming with SMAD and WNT inhibition generates patterned induced neurons (hpiNs).Transcriptional analyses showed that hpiN cultures contained cells along a developmental continuumranging from poorly differentiated neuronal progenitors to well-differentiated, excitatory glutamatergic neurons. The most differentiated neurons could be identified using a CAMK2A::GFP reporter gene. RNA sequencing analysis (population and single cell) over hpiNs differentiation time (D0 through D49 after induction). Two independent iPS lines, 9 time points, three replicates each.
创建时间：
2019-03-27
