Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in a ternary complex with COVOX-253 and COVOX-75 Fabs

Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in a ternary complex with COVOX-253 and COVOX-75 Fabs Descriptor: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, BROMIDE ION, ... Authors: Zhou, D, Zhao, Y, Ren, J, Stuart, D. Deposit date: 2020-12-24 Release date: 2021-03-03 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The antigenic anatomy of SARS-CoV-2 receptor binding domain. Cell, 184, 2021

严重急性呼吸综合征冠状病毒2（SARS-CoV-2）刺突糖蛋白受体结合域与COVOX-253、COVOX-75抗原结合片段（Fab）形成的三元复合物晶体结构。配体描述如下：1-(2-甲氧基乙氧基)-2-{2-[2-(2-甲氧基乙氧基)乙氧基]}乙烷、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-[α-L-岩藻吡喃糖-(1→6)]-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、溴离子…… 作者：Zhou, D、Zhao, Y、Ren, J、Stuart, D。 提交日期：2020-12-24，发布日期：2021-03-03，最后修改日期：2024-11-13。 实验方法：X射线衍射（分辨率2.5埃）。 引用文献：《SARS-CoV-2受体结合域的抗原结构》，Cell，184卷，2021年。