We developed a novel network inference approach, Biologically Anchored Knowledge Expansion (BAKE), to analyze large volume gene expression data obtained from a mouse model of insulin resistance progre
Background Clinical studies suggest that short-term insulin treatment in new-onset type 2 diabetes (T2DM) can promote prolonged glycemic control. The purpose of this study was to establish an animal m
We used streptozotocin-high fat diet (HFD) to induce T2D mouse model, and investigated the effect of standard chow diet and HFD on the composition and function of gut microbiota in them.
