Mitochondrial carrier homolog 2 (MTCH2) regulates the differentiation of AML cells by controlling pyruvate entry into the mitochondria, nuclear localization of pyruvate dehydrogenase complex and H3 and H4 histone acetylation
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE103834
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资源简介：
Inhibiting MTCH2 or the Mitochondrial Pyruvate Carrier increased levels of pyruvate and pyruvate dehydrogenase in the nucleus leading to differentiation and loss of stemness in AML. Gene expression analysis upon knock-down of MTCH2 by two independent shRNAs
创建时间：
2020-12-01
