Monika Zmojdzian, Jean Philippe Da Ponte, Krzysztof Jagla (2011) CIL:25537, Drosophila melanogaster, cardioblast (sensu Arthropoda), pericardial cell, cardiac outflow muscle, heart-anchoring cells, cephalic vascular rudiment cells. CIL. Dataset

The final morphogenesis of the cardiac outflow tract (OFT) depends on coordinated cell-cell interactions among the heart tip, migrating heart-anchoring cells (HANCs) and the dorsally growing cardiac outflow muscles (COMs). This is a three-dimensional reconstruction of the cardiac outflow tract (horizontal rotation) from stage-16 wild-type embryos stained for Ladybird early (Lbe; blue), Msp300 (green), and Myocyte enhancer factor 2 (Mef2; red). HANC cells (in blue) overlap dorsally the most anterior aorta. The COM muscles (in green) are attached on both sides to the most anterior Lbe-expressing cardioblasts (at this stage Lbe expression in the cardioblasts and pericardial cells is very week, and rendering Lbe signal visible resulted in an increased background). Note that ventrally to the tip of aorta are located cephalic vascular rudiment cells (cvr), which are Tin-positive, Dmef2-negative. Movie is SI Movie 1B in Proc Natl Acad Sci USA (2008) 105: 2475-2480. Movies from this publication include CIL# 25536, 25537, 25538, 25539, 25540, 25541.

心脏外流道的最终形态发生取决于心尖、迁移性心脏锚定细胞（HANCs）以及背侧生长的心脏外流肌（COMs）之间的协调细胞间相互作用。本图展示了对16期野生型胚胎进行Ladybird早期（Lbe；蓝色）、Msp300（绿色）和肌细胞增强因子2（Mef2；红色）染色的心脏外流道的三维重建（水平旋转）。HANC细胞（蓝色）在背侧与最前端的主动脉重叠。COM肌肉（绿色）在两侧附着于最前端表达Lbe的心肌祖细胞（在此阶段，心肌祖细胞和心包细胞的Lbe表达非常微弱，而Lbe信号的可见性导致背景增加）。请注意，在主动脉尖端的腹侧位于头部血管原基细胞（cvr），这些细胞Tin阳性，Dmef2阴性。该电影为Proc Natl Acad Sci USA（2008）第105卷第2475-2480页的SI Movie 1B。本出版物中的电影包括CIL# 25536、25537、25538、25539、25540、25541。