Analysis of a successful immune response against hepatitis C virus.
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Epitope-specific CD8+ CTL that recognize endogenously processed antigen were derived from liver biopsies taken 81 weeks following termination of HCV infection and expanded non-antigenically in vitro. The authors conclude that the ability to recover epitope-specific CTL from a healthy liver 1.5 yr after resolution of infection provides evidence for the existence of HCV-specific memory.
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1999-01-01



