DNA methylation profiling of pediatric central nervous system tumors in a Brazilian public healthcare setting

ChEBI2026-03-31 更新2026-07-12 收录

儿童肿瘤表观遗传学

DNA甲基化诊断分型

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-15074 数据链接链接失效反馈

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DNA methylation profiling of pediatric central nervous system tumors in a Brazilian public healthcare setting

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2026-03-31

Epigenetic footprint of hepatoblastoma defines a novel integrative molecular classification with clinical implications [RNA-seq]

母细胞瘤分子特征

儿童肿瘤表观遗传学

Hepatoblastoma (HB) is the predominant pediatric liver cancer with limited therapeutic options for patients with aggressive tumors. Nevertheless, it is a rare disease. Here, we performed a high-throug

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Additional file 7: Table S6. of DNA methylation analysis of paediatric low-grade astrocytomas identifies a tumour-specific hypomethylation signature in pilocytic astrocytomas

儿童肿瘤表观遗传学

甲基化DNA生物标志物

Three-way comparison of the test tumour set of pilocytic and diffuse astrocytomas with normal brain control tissue. 993 CpG probes are shown where the difference between the average beta values of pil

Figshare2016-12-14 更新40

DNA methylation changes at CpG and non-CpG sites are associated with development and clinical behavior in neuroblastoma [methylation]. Homo sapiens

神经母细胞瘤甲基化组

儿童肿瘤表观遗传学

DNA methylation changes in neuroblastoma, a clinically-heterogeneous pediatric tumor, have been described essentially in promoter regions. We analyzed the DNA methylome of neuroblastoma using high-den

NIAID Data Ecosystem30

Dynamic Chromatin Alteration Induces Oncogenic Hijacking by Essential Transcriptional Factors during Medulloblastoma Tumorigenesis [ATAC-Seq]

儿童肿瘤表观遗传学

染色质可及性与肿瘤发生

Using ATAC-seq analysis from GNPs to MBSHH we discovered a massive modification in chromatin accessibility during MBSHH formation. Next, using integrative bioinformatics, we identified genes of the nu

NIAID Data Ecosystem40

A specific form of cPRC1 containing CBX4 is co-opted to mediate oncogenic gene repression in diffuse midline glioma

儿童肿瘤表观遗传学

PRC1复合物功能调控

Diffuse midline glioma (DMG) is a fatal childhood brain tumour characterised primarily by mutant histone H3 (H3K27M). H3K27M causes a global reduction in Polycomb Repressive Complex 2 (PRC2)-mediated

Mendeley Data30

DNA methylation profiling of pediatric central nervous system tumors in a Brazilian public healthcare setting

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