Summary of studies measuring RDI-eIgG1 protection from LeTx challenge in rats.

Male 200 gram HSD were co-injected i.v. with LeTx (40 µg PA+12 µg LF) alone or in combination with RDI-eIgG1. Number of surviving animals in each study and the average time to death (in hours) is reported. Statistical analyses of survival curves (log-rank Mantel-Cox) and time-to-death (Student T-test) were performed using Prism (Graph Pad, Inc.).