five

Cinchona pubescens Transcriptome

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DataCite Commons2025-04-01 更新2025-04-09 收录
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https://datadryad.org/dataset/doi:10.5061/dryad.z34tmpgcc
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资源简介:
The enzymatic basis for quinine 1 biosynthesis was investigated. Transcriptomic data from the producing plant Cinchona pubescens led to the discovery of three enzymes involved in early and late steps of the pathway. A medium-chain alcohol dehydrogenase (CpDCS) and an esterase (CpDCE) yielded the biosynthetic intermediate dihydrocorynantheal 2 from strictosidine aglycone 3. Additionally, the discovery of an O-methyltransferase specific for 6´-hydroxycinchoninone 4 suggested the final steps order to be cinchoninone 16/17 hydroxylation, methylation and keto-reduction.
提供机构:
Dryad
创建时间:
2021-02-24
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