Chemical Inhibition of H3K27me3 demethylases during B cell differentiation
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https://www.ncbi.nlm.nih.gov/sra/SRP282900
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资源简介:
To understand the role of the H3K27me3 demethylases, UTX and JMJD3, in B cell differentiation. Naïve B cells were cultures ex vivo with LPS, IL-2,IL-5 in the presence of DMSO or GSK-J4, UTX/JMJD3 inhibitor. Plasmablasts and activated B cells were magnetically enriched after 3 days of culture. Overall design: RNAseq on B cells treated with GSK-J4 or DMSO
创建时间:
2022-01-15



