Microbiome profile of non-responding and responding periodontal pockets following non-surgical periodontal treatment

Periodontitis is a site-specific, chronic disease usually treated by non-surgical debridement of subgingival plaque. We aimed to determine the microbiome of sites that did not respond to this treatment (NR) compared with good responding (GR) sites before and after treatment. NR sites were not identifiable prior to treatment by clinical or microbiological parameters. Treatment failed to disrupt pathogenic bacterial community in NR sites.