Inflammatory type 2 conventional dendritic cells contribute to murine and human cholangitis

ChEBI2022-07-08 更新2026-07-12 收录

胆管炎免疫机制

树突状细胞亚型功能

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-11821 数据链接链接失效反馈

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Inflammatory type 2 conventional dendritic cells contribute to murine and human cholangitis

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2022-07-08

Inhibition of viral replication by XCR1- and XCR1+ cDC1

树突状细胞亚型功能

病毒免疫应答

In order to analyze whether type I and III IFN secreted by XCR1- and XCR1+ cDC1 inhibit viral replication, sorted XCR1- and XCR1+ cDC1 were stimulated with pIC for 12h. Supernatants were harvested and

NIAID Data Ecosystem40

Type I and type II interferon coordinately regulate suppressive dendritic cell fate and function during viral persistence

病毒持续性感染免疫抑制

树突状细胞亚型功能

We identified a population of immunosuppressive dendritic cells (iregDCs) that arises during LCMV-Cl13 infection. IregDCs have a distinct lineage, functional activity, and RNA expression profile compa

NIAID Data Ecosystem30

Table_1_CD8+XCR1neg Dendritic Cells Express High Levels of Toll-Like Receptor 5 and a Unique Complement of Endocytic Receptors.PDF

树突状细胞亚型功能

TLR5受体表达

Conventional dendritic cells (cDC) resident in the lymphoid organs of mice have been classically divided into CD8+ and CD8neg subsets. It is well-established that CD8+ dendritic cells (DCs) and their

NIAID Data Ecosystem20

CD4 + T-cell help explains clinical benefit of specific intra-tumoral dendritic cell states in human cancer

肿瘤免疫微环境

树突状细胞亚型功能

Classical type 1 dendritic cells (cDC1) have a low abundance in the tumor microenvironment (TME), but positively correlate with patient survival. We hypothesized that the ability of cDC1 to relay CD4+

NIAID Data Ecosystem40

Single cell RNA sequencing-based comparison of mouse splenic pDC, pDC-like cells, tDC, cDC1 and cDC2 at steady state and during a viral infection

树突状细胞亚型功能

病毒感染免疫应答

Plasmacytoid dendritic cells (pDC) are the main source of type I interferon (IFN) during viral infections. Their other functions are debated, due to a lack of tools to identify and target them in vivo

NIAID Data Ecosystem20

Inflammatory type 2 conventional dendritic cells contribute to murine and human cholangitis

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