Long term intrathecal administration of morphine vs baclofen: differences in CSF identified using multi-glycomics

CSF samples from patients that had long-term (>2years), intrathecal morphine or baclofen administered via an indwelling pump, and we performed proteomics and multi-glycomics via sequential release of polysialic acids, glycosaminoglycans, N-glycans and O-glycans from the same sample material.