Coordination Compounds for Biological Applications

In this proposal we present new hybrid crystalline materials based on a nitrogen-donor organic molecules and a biological active molecule, namely quercetin and morin. Materials were assembled with different transition metal cations depending on the final application, obtained by either microwave-assisted synthesis or under solvothermal conditions. Materials are obtained as microcrystalline powders or small-sized single crystals. For this reason, our in-house diffractometers have not been effective in the elucidation of the new crystal architectures. We believe that the high-resolution data collected at the BM01 and ID22 beamlines will allow us to unveil the crystalline structures of these materials. Because of their interesting application, the crystallographic data would help us to understand the biological activity of these bio-materials as well as the possible interactions that they create with different biological species (namely DNA and RNA).